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Protecting the Brain Through Natural Repair.

Protecting the Brain Through Natural Repair.Protecting the Brain Through Natural Repair.Protecting the Brain Through Natural Repair.

 A novel biologic therapy that activates and drives the brain’s natural repair systems to restore function at its source.

  Alzheimer’s disease and related dementias (ADRD) remain one of the biggest unmet needs in medicine, affecting tens of millions of people worldwide.


Despite decades of research, today’s therapies offer limited benefit and do little to address the underlying damage driving disease progression. Growing evidence points to neurovascular dysfunction as a central driver of neurodegeneration, opening the door to a fundamentally different way to treat disease.


Stream Biomedical is developing LG3, a first-in-class biologic designed to protect and restore the brain by activating its natural repair processes.

HOW LG3 RESTORES THE BRAIN’S NATURAL REPAIR SYSTEM

Protects &
Stabilizes Brain Cells

Protects &
Stabilizes Brain Cells

Protects &
Stabilizes Brain Cells

Blocks Inflammatory Cascades

Protects &
Stabilizes Brain Cells

Protects &
Stabilizes Brain Cells

Repairs the Blood-Brain Barrier

Protects &
Stabilizes Brain Cells

Repairs the Blood-Brain Barrier

Reactivates Natural Neurorepair

Protects &
Stabilizes Brain Cells

Repairs the Blood-Brain Barrier

Broad Impact Across Neurological Disease

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ADRD

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STROKE

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TRAUMATIC BRAIN INJURY

The Promise of a Regenerative Approach

Key Advantages of LG3

Key Advantages of LG3

Key Advantages of LG3

  • First-in-class biologic designed to activate the brain’s natural repair systems
  • Targets neurovascular dysfunction as an upstream driver of neurodegeneration
  • Engages multiple pathways involved in vascular integrity, inflammation, and neuronal recovery
  • Demonstrated activity across multiple preclinical models

Why it Matters

Key Advantages of LG3

Key Advantages of LG3

  • Represents a different approach to treating neurodegeneration
  • Aims to protect and restore the brain, not just slow decline
  • Potential across Alzheimer’s disease, stroke, and traumatic brain injury
  • Supported by strong mechanistic, preclinical, and published evidence

Stream Biomedical at Sachs Neuroscience Innovation Forum

Contact

Get in touch!

Stream Biomedical, Inc.

2450 Holcombe Boulevard, Suite J Houston, TX 77021

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