Turning Irreversible Into Recoverable.
A first-in-class recombinant biologic designed to activate the brain’s natural repair systems.
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A first-in-class recombinant biologic designed to activate the brain’s natural repair systems.
Neurodegenerative diseases affect tens of millions worldwide and remain one of the greatest unmet needs in medicine.
Today’s therapies are not designed to address neurovascular dysfunction — a central driver of pathology across neurological diseases including Alzheimer’s disease.
A new direction for neurodegenerative disease.

rLG3 is a first-in-class recombinant biologic derived from a natural protein (Perlecan) which activates the brain’s innate repair systems.
rLG3 engages multiple mechanisms involved in brain repair, recovery, and health.
This represents a fundamentally different approach to treating neurodegenerative disease.
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