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Turning Irreversible into Recoverable

Turning Irreversible into RecoverableTurning Irreversible into RecoverableTurning Irreversible into Recoverable


 A First-in-Class Biologic Therapy That Restores the Brain’s Natural Ability to 

Repair Itself After Injury or Disease 

 Each year, more than 90 million people worldwide experience stroke, traumatic brain injury, ALS and Alzheimer’s disease — conditions that cause lasting brain damage and loss of independence.

Despite decades of research, no approved therapy repairs the brain. Current treatments only slow decline or manage symptoms.

Stream Biomedical is developing LG3, a first-in-class regenerative biologic that reactivates the brain’s natural repair process. 

HOW LG3 RESTORES THE BRAIN’S NATURAL REPAIR SYSTEM

Protects &
Stabilizes Brain Cells

Protects &
Stabilizes Brain Cells

Protects &
Stabilizes Brain Cells

Blocks Inflammatory Cascades

Protects &
Stabilizes Brain Cells

Protects &
Stabilizes Brain Cells

Repairs the Blood-Brain Barrier

Protects &
Stabilizes Brain Cells

Repairs the Blood-Brain Barrier

Reactivates Natural Neurorepair

Protects &
Stabilizes Brain Cells

Repairs the Blood-Brain Barrier

Broad Potential Across Major Brain Injuries

#

STROKE

#

TRAUMATIC BRAIN INJURY

#

ALZHEIMER'S DISEASE

Demonstrated Neuroprotection in Preclinical Stroke Models

Stroke - PBS at Reperfusion

3D Visualization of neurovascular drop-out after experimental stroke in mice treated with saline (72 hours post-injury)

Stroke - LG3 at Reperfusion

3D Visualization of neurovascular protection of the same mice after treatment with LG3 (72 hours post-injury)

The Promise of a Regenerative Approach

Key Advantages of LG3

Key Advantages of LG3

Key Advantages of LG3

  • Restores natural repair pathways
  • Targets upstream drivers of damage
  • Shows consistent neuroprotection in rigorous models
  • Extends potential across major brain injuries 

Why it Matters

Key Advantages of LG3

Key Advantages of LG3

  • Addresses the root cause — neurovascular injury
  • Applicable across stroke, TBI, and neurodegenerative disease
  • Safe and effective in multiple preclinical models
  • Backed by 20+ peer-reviewed publications 

Contact

Get in touch!

Stream Biomedical, Inc.

2450 Holcombe Boulevard, Suite J Houston, TX 77021

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